Aiming at the problems of siltation promotion and siltation return in the beach area of Hangzhou Bay, a numerical calculation model of hydrodynamic and scour and siltation in the south bank of Ningbo Bay was constructed, and the harmoni headband reliability of the short-term scour and siltation numerical calculation model was verified by combining
Alison Reid, Juan Martin-Liberal, Charlotte Benson Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, UK Abstract: Patients with locally advanced or metastatic soft tissue sarcoma have a poor outlook with median survival in the order of 1 year.There is therefore an urgent need for novel agents to impact this disease.Trabectedin is one su
Migrating eastern North American monarch butterflies use a time-compensated sun compass to adjust their flight to the southwest direction.Although the antennal genetic circadian clock and the azimuth of the sun are instrumental for proper function of the compass, it is unclear how these signals are represented on a neuronal level and how they are i
Abstract Protein arginine methyltransferase 5 (PRMT5) catalyzes mono-methylation and symmetric di-methylation on arginine residues and has emerged as a potential antitumor target with inhibitors being tested in clinical trials.However, it remains unknown how moonbon the efficacy of PRMT5 inhibitors is regulated.Here we report that autophagy blockag